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Reaction catalyst for cross-coupling and method for manufacturing aromatic compound

机译:用于交叉偶联的反应催化剂和制备芳族化合物的方法

摘要

The object of the present invention is to provide a new organic phosphorus ligand that can efficiently promote cross-coupling reaction to obtain the target substance at high yield, as well as a method of manufacturing such ligand whose steric characteristics and electronic characteristics can be fine-tuned and which can be used to cause cross-coupling reaction at high yield. As a means for achieving the aforementioned object, a phosphine compound expressed by General Formula (1) below is provided.; embedded image (In the formula, R1 and R2 are each independently a secondary alkyl group, tertiary alkyl group, or cycloalkyl group, while R3 and R4 are each independently a hydrogen, aliphatic group, heteroaliphatic group, aromatic group, alicyclic group, or heterocyclic group. Note that R3 and R4 have no phosphorus atom and that R3 and R4 are not both hydrogen at the same time).
机译:本发明的目的是提供一种新型的有机磷配体,该配体可以有效地促进交叉偶联反应,以高收率获得目标物质,以及一种制备这种配体的方法,该配体的空间特性和电子特性可以是精细的。调整后可用于引起高产率的交叉偶联反应。作为实现上述目的的手段,提供以下通式(1)表示的膦化合物。 “嵌入式图像” (在式中,R 1 和R 2 分别独立地是仲烷基,叔烷基或环烷基,而R 3 和R 4 分别独立地为氢,脂族基,杂脂族基,芳族基,脂环族基或杂环基。请注意,R 3 和R 4 < / Sup>没有磷原子,并且R 3 和R 4 都不同时是氢。

著录项

  • 公开/公告号US9707551B2

    专利类型

  • 公开/公告日2017-07-18

    原文格式PDF

  • 申请/专利权人 HOKKO CHEMICAL INDUSTRY CO. LTD.;

    申请/专利号US201414762456

  • 发明设计人 NOBUMICHI KUMAMOTO;KENTA SUZUKI;

    申请日2014-01-23

  • 分类号C07D209/82;C07C209/10;B01J31/24;C07D295/02;C07F9/50;C07F9/54;C07C1/32;C07C41/30;C07C253/30;C07D295/033;

  • 国家 US

  • 入库时间 2022-08-21 13:46:13

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