Cerclage pessary containing progesterone prolonged release, sustained and continuous, useful for the Prevention of Preterm Birth.

摘要

Cerclage progesterone pessary containing homogeneously distributed in the body, providing a prolonged release of the pessary, sustained and continuous for a period of at least 6 months, where the pessary is composed of Elastomers with dimethylsiloxane mechanism RTV (room temperat ERUs Vulcanization), the amount of progesterone is between 20% to 30% w / WThe Weight of the pessary and the proportions of the Polymers that form the Matrix, is between 6 to 14: 1: 1. The pessary cerclage is useful for the Prevention of Preterm Birth.Progesterone diffuses through the polymer continuously, without altering the shape and Integrity of the pessary, given that the elastomer to form the polymeric matrix used in the present Invention, it is not biodegradable. This ensures that the shape of the pessary is kept intact until the end of treatment.