TRANSTIRETINAL (TTR) AMYLOIDOSIS THERAPY WITH ANTIBODIES AND ALSO ANTIBODIES RECEIVED FROM HUMAN FOR THE INDICATED THERAPY

摘要

Proposed new antibodies, derived from humans, are specific for transthyretin (TTP), preferably capable of binding with incorrectly folded, improperly assembled and / or aggregated forms of TTP, as well as methods based on these antibodies. In addition, methods for the diagnosis and / or control of diseases and treatment options for diseases associated with TTP amyloidosis have been proposed. Analyzes and kits based on antibodies specific to TTP or deposits and TTP aggregates have also been proposed. New antibodies against TTP can be used in pharmaceutical and diagnostic compositions for targeted immunotherapy and diagnosis of TTP.