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STABILIZATION OF IMMUNOHLOBULINS WITH THE HELP OF WATER COMPOSITION WITH HYSTIDINE AT pH FROM LOW ACID TO NEUTRAL
STABILIZATION OF IMMUNOHLOBULINS WITH THE HELP OF WATER COMPOSITION WITH HYSTIDINE AT pH FROM LOW ACID TO NEUTRAL
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机译:在低酸至中性pH值条件下,稳定的免疫球蛋白可与组氨酸一起组成水
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摘要
The present invention provides, along with other aspects, storage-stable aqueous formulations of immunoglobulins with histidine at a pH ranging from weakly acid to neutral. The present invention also provides methods for stabilizing immunoglobulin compositions by preparing them with histidine at a pH in the range from weakly acid to neutral. Advantageously, the methods and compositions described in this application allow to obtain stable aqueous compositions of immunoglobulins at a pH in the range from weakly acid to neutral, suitable for parenteral administration.
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