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SUBSTITUTED PHTHALAZIN-1(2H)-ONE DERIVATIVES AS SELECTIVE INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE-1

机译:取代的酞菁-1(2H)-1衍生物作为聚(ADP-核糖)聚合酶-1的选择性抑制剂

摘要

The present invention relates to novel compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to a process of preparing novel compounds of general formula (I), their stereoisomers, regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.
机译:本发明涉及通式(I)的新型化合物,其立体异构体,区域异构体,互变异构形式和参与其合成的新型中间体,其药学上可接受的盐,药学上可接受的溶剂化物和包含它们的药物组合物。本发明还涉及制备通式(I)的新型化合物,其立体异构体,区域异构体,其互变异构形式,其药学上可接受的盐,药学上可接受的溶剂化物,包含它们的药物组合物以及参与其合成的新颖中间体的方法。

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