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CARBOCYCLIC NUCLEOSIDES WITH A FUNCTIONALIZED NORBORNANE RADICAL REPLACING GLYCOSIDIC FRAGMENT

机译:功能化的降硼烷自由基取代糖苷片段的碳环核苷酸

摘要

The invention relates to derivatives of (+)-, (-)- optically active carboxylic or racemic nucleosides to be used as viral and/or antitumoral agents. According to the invention, the derivatives have a general formula I, comprising, as heterocyclic base, adenine or adenine substituted in the 6 position or 6-alkoxypurine (RRN is an etheric group OR) and a norbornane radical with specific functionalization, as glycosidic rest.
机译:本发明涉及用作病毒和/或抗肿瘤剂的(+)-,(-)-旋光羧酸或消旋核苷的衍生物。根据本发明,所述衍生物具有通式I,其包含在6位上取代的腺嘌呤或腺嘌呤或6-烷氧基嘌呤(RRN是醚基OR)和具有特定官能化的降冰片烷自由基作为糖苷残基作为杂环碱。 。

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