An isolated protein structure comprising an amino acid sequence that has at least 75% identity of SEQ ID NO: 16, which has 7 strains and 6 loops between the strains, and which comprises the amino acid sequence SEQ ID NO: 16, but in which one or more of the loops are altered to bind to a target while the strains maintain their sequence as trunk portions, in which the loops are in residues 13-16, 22-28, 38-43, 51-54, 60-64 and 75-81 of SEQ ID NO: 16 and are capable of binding with cellular proteins and / or nucleic acid molecules.
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机译:一种分离的蛋白质结构,其包含与SEQ ID NO:16具有至少75%同一性的氨基酸序列,其具有7个菌株和菌株之间的6个环,并且包含氨基酸序列SEQ ID NO:16,但是其中改变一个或多个环以结合至靶标,同时菌株将其序列保持为树干部分,其中环位于残基13-16、22-28、38-43、51-54、60-64和SEQ ID NO:16的75-81,并且能够与细胞蛋白和/或核酸分子结合。
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