Compositions and methods comprising cellulase variants with reduced affinity for non-cellulosic materials

摘要

An isolated cellulase variant, where said variant is a mature form that has cellulase activity, and where said variant is a variant of a parent cellulase whose amino acid sequence is at least 97% identical to the amino acid sequence of SEQ ID NO : 3, the variation consisting of a substitution at position 63 numbered by correspondence with the amino acid sequence of SEQ ID NO: 3, and where the substitution causes the cellulase variant to have a more negative net charge compared to the sequence of amino acids of SEQ ID NO: 3.