DIFFERENT SEROTYPES OF VESICULAR STOMATITIS VIRUS AS EXPRESSION VECTORS FOR IMMUNIZATION REGIMENS

摘要

Immunization platforms, immunization regimes and medicaments useful forinducing an immune response in amammal and preventing or treating a pathogenic infection in a mammal, whereinsaid immunization platforms and medicamentscomprise a recombinant vesicular stomatitis virus (VSV) of one serotype and arVSV of another serotype and are used in a prime-boostimmunization regime In aspects of the invention one VSV serotype is Indianaand the other VSV serotype is New Jersey.