DIFFERENT SEROTYPES OF VESICULAR STOMATITIS VIRUS AS EXPRESSION VECTORS FOR IMMUNIZATION REGIMENS

摘要

There is provided an immunization platform, immunization therapy, and medicament useful for inducing an immune response in a mammal and for preventing or treating a pathogenic infection in a mammal, said immunization platform and medicament comprising a serotype of recombinant vesicular stomatitis virus (rVSV) And rVSV of other serotypes, and are used in prime boost immunization regimens. In an embodiment of the invention, one VSV serotype is Indiana and the other VSV serotype is New Jersey.