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OVARIAN CANCER MARKER AND OVARIAN CANCER DETECTION METHOD

机译:卵巢癌标志物和卵巢癌检测方法

摘要

Provided are: an ovarian cancer marker, i.e., a glycoprotein, which has high sensitivity and specificity and enables the easy discrimination of ovarian cancer from endometriosis; and an ovarian cancer detection method using the ovarian cancer marker.An ovarian cancer marker which comprises a glycoprotein containing α-chains of a complement factor 4-binding protein, said marker being characterized in that at least one of the α-chains has one or more N-binding sugar chains and at least one of the N-binding sugar chains contains an equal number of galactose moieties and sialic acid moieties.
机译:提供:卵巢癌标志物,即糖蛋白,其具有高敏感性和特异性,并使得能够容易地将卵巢癌与子宫内膜异位症区分开。以及使用卵巢癌标记物的卵巢癌检测方法。卵巢癌标志物,其包含糖蛋白,所述糖蛋白含有补体因子4结合蛋白的α链,所述标志物的特征在于,至少一个α链具有一个或多个N结合糖链,并且至少一个α链具有N个结合糖链。 N-结合糖链包含相等数量的半乳糖部分和唾液酸部分。

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