mPGES-1 TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS

摘要

This disclosure relates to compounds of formula (I) as mPGES-I inhibitors, and pharmaceutically acceptable salts thereof. These compounds are inhibitors of the microsomal prostaglandin E synthetase-1 (mPGES-1) enzyme and are thus useful for the treatment of pain and / or inflammation from a variety of diseases or conditions such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain, . / RTI