COMPOSITION FOR PREVENTING OR TREATING CARDIOVASCULAR DISEASES CONTAINING P32 INHIBITOR

摘要

The present invention relates to a composition for preventing or treating cardiovascular diseases, and more specifically, to a composition for preventing or treating cardiovascular diseases containing a p32 inhibitor as an effective component. The p32 inhibitor according to the present invention has an effect of inhibiting arginase activity, and has an activity of increasing an L-arginine production level, decreasing the calcium concentration of mitochondria, and increasing the phosphorylation of CaMKII through the inhibition of arginase activity. Therefore, the composition containing the p32 inhibitor as an effective component can be effectively used as a therapeutic agent for the prevention or treatment of cardiovascular diseases.;COPYRIGHT KIPO 2017