首页> 外国专利> COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR IMMUNE DISEASES COMPRISING EXTRACT OF HYDROPONIC GINSENG OR COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENT

COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR IMMUNE DISEASES COMPRISING EXTRACT OF HYDROPONIC GINSENG OR COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENT

机译:用于预防或治疗炎症性疾病或免疫疾病的组合物,其中包括人参的提取物或复方的复方活性成分

摘要

The present invention relates to a composition for preventing or treating inflammatory diseases or immune diseases comprising an extract of hydroponic ginseng or a compound isolated therefrom as an active ingredient. The extract of hydroponic ginseng or a ginsenoside Re compound isolated therefrom according to the present invention has an excellent activity of suppressing the production of pro-inflammatory cytokine, IL-1β, caused by stimulating factors inducing inflammatory reactions in macrophages and dendritic cells; and suppresses the activity of NLRP3 inflammasome known to be involved in pathogenesis of various inflammatory diseases, and thus can be beneficially used in the development of therapeutic agents for inflammatory diseases and immune diseases that may be induced by excessive inflammatory reactions. Further, since the extract of hydroponic ginseng and a ginsenoside Re compound isolated therefrom are originated from an edible natural substance, it causes no cytotoxicity in cells and is safe in the human body, and thus can be safely used as a material for drugs as well as functional health foods.;COPYRIGHT KIPO 2017
机译:本发明涉及用于预防或治疗炎性疾病或免疫疾病的组合物,其包含水培人参提取物或从中提取的化合物作为活性成分。根据本发明的水培人参提取物或人参皂苷Re化合物的提取物具有优异的抑制促炎细胞因子IL-1β产生的活性,所述促炎细胞因子IL-1β是由在巨噬细胞和树突状细胞中诱导炎症反应的刺激因子引起的。并且抑制已知参与多种炎性疾病的发病机理的NLRP3炎性体的活性,因此可以有益地用于开发由过度的炎性反应诱导的炎性疾病和免疫性疾病的治疗剂。此外,由于水培人参提取物和从中分离出的人参皂苷Re化合物源自可食用的天然物质,因此它不会对细胞产生细胞毒性,并且对人体安全,因此也可以安全地用作药物原料。作为功​​能性保健食品。; COPYRIGHT KIPO 2017

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