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APPARATUS AND METHOD FOR ASSESSING EFFECTS OF DRUGS BASED ON NETWORKS
APPARATUS AND METHOD FOR ASSESSING EFFECTS OF DRUGS BASED ON NETWORKS
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机译:基于网络的药物作用评估装置和方法
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摘要
The present invention relates to an apparatus and a method for evaluating drug efficacy of a network, and more particularly, to a method and apparatus for evaluating drug efficacy of a network based on at least one of inference based on drug adjacency or proximity to disease and inference based on distance between a gene module and disease Generating a classifier that determines whether a relationship between a drug and a disease is to be determined using a learning technique that takes the association as a feature, and determining whether the drug and the disease are related using the classifier, Based on a database of interactions and databases built on protein and gene relevance databases, you can search for drug-to-disease relationships that show drug efficacy, and evaluate the molecular response of drugs to create more precise and sensitive new drug efficacy The time and cost required to develop and discover new drugs It can be reduced.
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