DOWN REGULATION OF TRANSCRIPTION OF SINE/ALU RETROTRANSPOSONS FOR INDUCING OR RECOVERY OF PROLIFERATION AND/OR PLURIPOTENCY OF STEM CELL

摘要

FIELD: biotechnologies.;SUBSTANCE: invention relates to biotechnology. Method involves reduction of level or activity of transcripts of SINE/Alu retrotransposons in cell in amount sufficient for inducing or recovery of proliferation ability and/or pluripotency of specified mammal cell.;EFFECT: method of inducing and/or recovery and/or maintenance of phenotype without signs of aging or its aspects is described, in particular ability of proliferation and/or pluripotency in mammal cell.;25 cl, 58 dwg, 9 tbl, 3 ex