Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

Vasundhra Kashyap; Naira C. Rezende; Kymora B. Scotl; Sebastian M. Shaffer; Jenny Liao Persson; Lorraine J. Gudas; Nigel P. Mongan

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Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

机译：干细胞多能性和分化的调节涉及与polycomb抑制复合物和干细胞microRNA的nanog，OCT4和SOX2多能性转录因子的相互调节电路。

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*These authors contributed equally.

机译：* 这些作者做出了同等贡献。

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《Stem Cells and Development》 |2009年第7期|1093-1108|共16页
作者
Vasundhra Kashyap; Naira C. Rezende; Kymora B. Scotl; Sebastian M. Shaffer; Jenny Liao Persson; Lorraine J. Gudas; Nigel P. Mongan;
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Department of Pharmacology, Weill Cornell Medical College, New York, New York.|Graduate Programs in Pharmacology, Weill Cornell Medical College, New York, New York.;

Department of Pharmacology, Weill Cornell Medical College, New York, New York.|Graduate Programs in Molecular and Cell Biology, Weill Cornell Medical College, New York, New York.;

Department of Pharmacology, Weill Cornell Medical College, New York, New York.|Graduate Programs in Tri-Institutional MD-PhD Program, Weill Cornell Medical College, New York, New York.;

Department of Pharmacology, Weill Cornell Medical College, New York, New York.|Graduate Programs in Neuroscience, Weill Cornell Medical College, New York, New York.;

Division of Experimental Cancer Research, Department of Laboratory Medicine, Clinical Research Center Lund University, University Hospital, Malm?, Sweden.;

Department of Pharmacology, Weill Cornell Medical College, New York, New York.;

Department of Pharmacology, Weill Cornell Medical College, New York, New York.;

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1. Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. [J] . Kashyap V, Rezende NC, Scotland KB Stem cells and development . 2009,第7期

机译：干细胞多能性和分化的调控涉及NANOG，OCT4和SOX2多能性转录因子与多梳抑制复合物和干细胞microRNA的相互调控。
2. Superoxide dismutase 1 expression is modulated by the core pluripotency transcription factors Oct4, Sox2 and Nanog in embryonic stem cells [J] . Solari Claudia, Victoria Petrone Maria, Vazquez Echegaray Camila, Mechanisms of Development . 2018,第期

机译：超氧化物歧化酶1表达由胚胎干细胞中的核心多能转录因子调节Oct4，Sox2和Nanog
3. Regulatory Circuitries Coordinated by Transcription Factors and microRNAs at the Cornerstone of Hematopoietic Stem Cell Self-Renewal and Differentiation. [J] . Starnes LM, Sorrentino A Current stem cell research & therapy . 2011,第2期

机译：在造血干细胞自我更新和分化的基石上，转录因子和microRNA协调的调节电路。
4. Inference of Transcriptional Network for Pluripotency in Mouse Embryonic Stem Cells [C] . S Aburatani International Conference on Mathematical Modeling in Physical Sciences . 2015

机译：小鼠胚胎干细胞中多能性转录网络推断
5. Analysis of pluripotent mouse stem cell proteomes: Insights into post-transcriptional regulation of pluripotency and differentiation. [D] . O'Brien, Robert Norman. 2010

机译：多能小鼠干细胞蛋白质组学分析：对多能性和分化的转录后调控的见解。
6. Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog OCT4 and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs [O] . Vasundhra Kashyap, Naira C. Rezende, Kymora B. Scotland, -1

机译：干细胞多能性和分化的调节涉及与polycomb抑制复合物和干细胞microRNA的nanogOCT4和SOX2多能性转录因子的相互调节电路。
7. Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs [O] . Kashyap, Vasundhra, Rezende, Naira C., Scotland, Kymora B., 2009

机译：干细胞多能性和分化的调节涉及与polycomb抑制复合物和干细胞microRNA的nanog，OCT4和SOX2多能性转录因子的相互调节电路。

Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

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