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METHOD FOR TREATMENT OF LOCALLY SPREAD UNRESECTABLE ESOPHAGEAL CANCER

机译:局部扩散性无法治愈的食管癌的治疗方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to oncology, and can be applied for treatment of locally spread unresectable esophageal cancer. For this purpose in conditions of procedure room after processing chest skin with antiseptic solution patients receive intradermally by 0.3 ml of autologous dendritic-cell vaccine, two injections from each side of chest approximately between III and IV, IV and V ribs. Dose constitutes 5,000,000 dendritic cells. 2 weeks after introduction of first vaccine second dendritic-cell vaccine is introduced in the same dose. 2 weeks after introduction of second vaccine third dendritic-cell vaccine is introduced in total dose 10,000,000 dendritic cells. 2 weeks after third introduction of vaccine fourth dendritic-cell vaccine is introduced in total dose 10,000,000 dendritic cells. During the entire course of vaccine therapy patients receive 30,000,000 cells.;EFFECT: invention makes it possible to increase duration and to improve quality of life in patients with locally spread unresectable esophageal cancer.;1 ex
机译:技术领域本发明涉及医学,即肿瘤学,可用于治疗局部扩散的不可切除的食管癌。为此目的,在用消毒液处理胸部皮肤后的手术室条件下,患者通过皮内注射0.3 ml自体树突状细胞疫苗,从胸部的每一侧进行两次注射,大约在III和IV,IV和V肋之间。剂量构成5,000,000树突状细胞。引入第一种疫苗后2周,以相同剂量引入第二种树突状细胞疫苗。引入第二种疫苗后2周,总剂量为10,000,000的树突状细胞被引入了第三种树突状细胞疫苗。第三次引入疫苗后2周,以总剂量10,000,000个树突细胞引入了第四种树突状细胞疫苗。在疫苗治疗的整个过程中,患者会接受30,000,000个细胞。效果:本发明可以延长局部切除的食管癌患者的病程并提高其生活质量。1

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