METHOD OF COMBINED TREATMENT OF PATIENTS WITH LOCALLY SPREAD RESECTABLE ESOPHAGEAL CANCER

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to oncology and can be used for treatment of locally spread resectable esophageal cancer. Method includes radical surgery, polychemotherapy and radiotherapy. Before operation 2 courses of polychemotherapy are carried out in accordance with the scheme: cysplatin 50 mg/m² 1,8 day, gemcitabine -800 mg/m² intravenously drop-by-drop during half-hour infusion - 2, 9 days with 3-week long interval between courses. After that, surgical intervention in radical volume with two-zonal 2F lymphodissection, with carrying out IORT in single dose 10 Gy onto the bed of removed tumour and ways of regional metastasis. In post-operational period additionally course of DGT is carried out on cervical, supraclavicular zones in TFD -40 Gy.;EFFECT: application of invention makes it possible to increase efficiency of combined treatment due to prevention of tumour process progression and distant metastasis and reduction of number of post-operational complications.;1 ex