L-LYSINE-PRODUCING CORYNEFORM BACTERIUM WITH MUTANT GENE FUSA AND METHOD FOR OBTAINING L-LYSINE WITH APPLICATION THEREOF

摘要

FIELD: medicine.;SUBSTANCE: group of the inventions relates to field of biotechnology. Claimed is L-lysine-producing bacterium of genus Corynebacterium, modified in such a way that amino acid substitution H461Q is contained in amino acid sequence of product of mutant gene fusA. Claimed is L-lysine-producing bacterium of genus Brevibacterium, modified in such a way that amino acid substitution H461Q is contained in amino acid sequence of product of mutant gene fusA. Claimed is method for obtaining L-lysine, which includes cultivation of any of said modified bacteria.;EFFECT: group of inventions makes it possible to increase level of L-lysine production in said strains-producents by not less than 9% in comparison with parential strains-producents of L-lysine.;3 cl, 1 tbl, 3 ex