AGING MACULAR DEGENERATION MODEL ANIMAL OF NONHUMAN PRIMATE AND ITS CREATION METHOD

摘要

PROBLEM TO BE SOLVED: To provide a method of creating an AMD model animal of a nonhuman primate, and a method of evaluating an effect of a test substance for the prevention or the treatment of the AMD and a method of screening the substance having the effect of the prevention or the treatment of the AMD by using the AMD model animal created by the method.;SOLUTION: A method of creating an AMD model animal is characterized by administering a sodium Iodate in a vitreous body of an animal individual of a nonhuman primate. Also, the AMD model animal of the nonhuman primate is created by the method of creating the AMD model animal. By using the created AMD model animal, a method of evaluating an effect of the test substance for prevention or treatment of the AMD is provided for evaluating the prevention or treatment effect of the AMD of the test substance.;SELECTED DRAWING: None;COPYRIGHT: (C)2019,JPO&INPIT