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Application of alkaloids in the preparation of pharmaceutical compositions for the prevention or treatment of pulmonary fibrosis

机译:生物碱在制备预防或治疗肺纤维化的药物组合物中的应用

摘要

Disclosed is a new use of a compound as indicated in structural formula I in preparing medications for preventing and/or treating pulmonary fibrosis. The compound having the structure as indicated in structural formula 1 substantially reduces the inflammation of diseased lung tissue, lowers the concentration of fibrosis factors TGF-²l in diseased lung tissue, decreases the excessive deposition of collagen in diseased lung tissue, and has substantial prevention and treatment effectiveness against fibrosis.
机译:公开了如结构式I所示的化合物在制备用于预防和/或治疗肺纤维化的药物中的新用途。具有结构式1所示结构的化合物大大减少了患肺组织的炎症,降低了患肺组织中纤维化因子TGF-βl的浓度,减少了患肺组织中胶原蛋白的过量沉积,并具有实质性的预防和预防作用。对抗纤维化的治疗效果。

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