首页>
外国专利>
RECOMBINANT PROTEIN FOR PREVENTION OR TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS
RECOMBINANT PROTEIN FOR PREVENTION OR TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS
The present invention relates to a recombinant protein for prevention or treatment of idiopathic pulmonary fibrosis, which is recombined on the basis of milk fat globule-EGF factor 8(MFG-E8) and has the amino acid sequence of SEQ ID NO: 1. The recombinant protein can fundamentally treat a lung tissue that has undergone fibrosis due to idiopathic pulmonary fibrosis and as such, can recover lung function to a normal level. In addition, the present invention relates to a pharmaceutical composition comprising as an active ingredient a recombinant protein for prevention or treatment of idiopathic pulmonary fibrosis, which is recombined on the basis of milk fat globule-EGF factor 8(MFG-E8) and has the amino acid sequence of SEQ ID NO: 1.
展开▼
机译:本发明涉及用于预防或治疗特发性肺纤维化的重组蛋白,其在乳脂球-EGF因子8(MFG-E8)的基础上重组,并具有SEQ ID NO:1的氨基酸序列。重组蛋白可以从根本上治疗由于特发性肺纤维化而发生纤维化的肺组织,因此可以使肺功能恢复到正常水平。此外,本发明涉及一种药物组合物,其包含作为预防或治疗特发性肺纤维化的重组蛋白作为活性成分,所述重组蛋白基于乳脂球-EGF因子8(MFG-E8)重组并且具有SEQ ID NO:1的氨基酸序列。
展开▼