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Compound and analogues for tracing histone acetylation inhibitors PET imaging for diagnosis and treatment of tumors
Compound and analogues for tracing histone acetylation inhibitors PET imaging for diagnosis and treatment of tumors
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机译:用于追踪组蛋白乙酰化抑制剂的化合物和类似物PET显像以诊断和治疗肿瘤
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摘要
The present invention relates to a group of compounds for nuclear medicine imaging through F-18 labeled histone acetylation inhibitors (HDACi) of indole or indoline benzoyl amine and its derivatives, and provides a series of nuclear medicine imaging agents that bind with HDAC overexpression in vivo for diagnosis of malignant tumors discovered in the nuclear medicine imaging tracing.
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