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Selective high affinity α3β4 nicotinic acetylcholine receptor antagonists
Selective high affinity α3β4 nicotinic acetylcholine receptor antagonists
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机译:选择性高亲和力α3β4烟碱乙酰胆碱受体拮抗剂
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摘要
Provided herein are novel and selective high affinity α3β4 nicotinic acetycholine receptor ligands and pharmaceutical compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, drug addiction or pain using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of selectively antagonizing receptors such as, for example, the α3β4 nicotinic acetycholine receptor using the compounds and compositions disclosed herein.
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