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Method of preparing lyophilized powder for injection comprising aloe and Panax pseudo-ginseng

机译:包含芦荟和人参的注射用冻干粉的制备方法

摘要

A method of preparing a lyophilized powder for injection, including: (1) weighing and mixing aloe powder and Panax pseudo-ginseng powder to yield an active pharmaceutical ingredient, and mixing the active pharmaceutical ingredient and distilled water to yield a mixed aqueous solution; (2) stiffing the mixed aqueous solution to enable the aloe power and the Panax pseudo-ginseng powder to be completely dissolved, and then allowing the mixed aqueous solution to stand; (3) collecting, filtering, and clarifying a supernate obtained in (2); (4) adding hydrochloric acid to a filtrate obtained in (3) to adjust the pH value of the filtrate, heating and sterilizing the filtrate, and then naturally cooling the filtrate, to yield a cooled liquid; (5) adding hydrochloric acid to the cooled liquid to adjust the pH value of the cooled liquid, filtering the cooled liquid and collecting a pharmaceutical solution; and (6) packaging and lyophilizing the pharmaceutical solution.
机译:一种制备注射用冻干粉的方法,该方法包括:(1)称量并混合芦荟粉和 Panax假-人参粉末以产生活性药物成分,并将其混合。活性药物成分和蒸馏水产生混合水溶液; (2)使混合水溶液变硬,以使芦荟粉和 Panax假-人参粉完全溶解,然后使其静置; (3)收集,过滤和澄清在(2)中获得的上清液; (4)在(3)中得到的滤液中加入盐酸以调节滤液的pH值,将滤液加热灭菌,然后自然冷却,得到冷却液; (5)在冷却液中加入盐酸以调节冷却液的pH值,过滤冷却液并收集药液; (6)包装和冻干药物溶液。

著录项

  • 公开/公告号US10016366B2

    专利类型

  • 公开/公告日2018-07-10

    原文格式PDF

  • 申请/专利权人 RONGXUAN ZHANG;

    申请/专利号US201615011450

  • 发明设计人 RONGXUAN ZHANG;

    申请日2016-01-29

  • 分类号A61K9/19;A61K9;A61K36/258;A61K36/886;

  • 国家 US

  • 入库时间 2022-08-21 13:04:13

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