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Compounds having triple activities of thrombolysis, antithrombosis, and radical scavenging, synthesis, and use thereof

机译:具有溶栓,抗血栓形成和自由基清除,合成及其用途的三重活性的化合物及其用途

摘要

The present invention relates to a compound simultaneously having triple activities of thrombolysis, antithrombosis and free radical scavenging, as well as the preparation method, composition, and applications thereof. The compound is represented by the formula I shown below:; embedded image wherein the definitions of T, Q, R1 and R2 are described herein. The compound of the present invention simultaneously has triple functions of thrombolysis, free radical scavenging and thrombus-targeting/antithrombosis. The present invention also relates to a pharmaceutical composition comprising the compound, and a preparation method and a nanostructure of the compound.
机译:本发明涉及同时具有溶栓,抗血栓形成和自由基清除三重活性的化合物,及其制备方法,组合物和应用。该化合物由下式I表示: “嵌入式图像” 其中描述了T,Q,R 1 和R 2 的定义。本发明的化合物同时具有溶栓,清除自由基和靶向血栓/抗血栓形成的三重功能。本发明还涉及包含该化合物的药物组合物,以及该化合物的制备方法和纳米结构。

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