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FABRICATION OF A DEVICE FOR SINGLE-MOLECULE DNA SEQUENCING USING SIDEWALL LITHOGRAPHY

机译:利用侧壁光刻技术制备单分子DNA测序的装置

摘要

A nanochannel DNA sequencing device and related methods of fabrication and of DNA sequencing are provided. In one example, a device may include a nanochannel having a width of no greater than about 2 nm and a height no greater than 1.5 times the width. The device may further include a pair of electrodes having a width of no greater than about 10 nm, the electrodes being exposed within the nanochannel to measure electronical characteristics of a DNA strand passing through the nanochannel. In one example, the nanochannel may be formed using lithography techniques, such as sidewall lithography.
机译:提供了一种纳米通道DNA测序设备以及相关的制造方法和DNA测序。在一实例中,装置可包含纳米通道,其宽度不大于约2nm且高度不大于宽度的1.5倍。该装置可以进一步包括一对宽度不大于约10nm的电极,该电极暴露在纳米通道内以测量穿过纳米通道的DNA链的电子特性。在一实例中,可使用诸如侧壁光刻之类的光刻技术来形成纳米通道。

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