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Vaccines against pregnancy-associated malaria

机译：预防妊娠相关疟疾的疫苗

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摘要

The present invention relates to combinations of polypeptides or of polynucleotides corresponding to a specific region of the N-terminal portion of the VAR2CSA protein of different parasitic families or lines of Plasmodium falciparum, and to their use in the prevention of pregnancy-associated malaria. The invention also relates to immunogenic compositions and to vaccines useful for preventing malaria in pregnant women.

机译：本发明涉及与恶性疟原虫的不同寄生虫家族或品系的VAR2CSA蛋白的N-末端部分的特定区域对应的多肽或多核苷酸的组合，及其在预防中的用途与妊娠有关的疟疾。本发明还涉及用于预防孕妇疟疾的免疫原性组合物和疫苗。 展开▼

著录项

公开/公告号US9855321B2

专利类型

公开/公告日2018-01-02

原文格式PDF

申请/专利权人 INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT (IRD);
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申请/专利号US201414762300

发明设计人 NICAISE TUIKUE NDAM;PHILIPPE DELORON;JUSTIN DORITCHAMOU;
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申请日2014-01-21

分类号A61K39/015;A61K39;C07K14/445;

国家 US

入库时间 2022-08-21 12:55:48

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3. VACCINES AGAINST PREGNANCY-ASSOCIATED MALARIA [P] . 欧洲知识产权局专利： EP2598173B1 . 2018-04-18

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4. Vaccines against pregnancy-associated malaria [P] . 美国专利： US9540425B2 . 2017-01-10

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5. VACCINES AGAINST PREGNANCY-ASSOCIATED MALARIA [P] . AP4023A . 2017-02-02

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