A chimeric influenza virus hemagglutinin (ha) polypeptide,an immunogenic composition comprising same and uses thereof

摘要

Provided herein are flu hemagglutinin polypeptides, including chimeric influenza virus hemagglutinin polypeptides, and flu hemagglutinin polypeptides comprising modified glycosylation sites and non-naturally glycosylation sites, compositions comprising the same, vaccines comprising the same and methods of their use.