A PROCESS FOR EXTRACTION OF NOVEL PROTEIN LOLDUVIN S63 FROM INDIAN SQUID LOLIGO DUVAUCELI AND PRODUCT THEREOF

摘要

This is the first discovery done in India to isolate and identify a new protein named as Lolduvin-S from the ink of the Indian squid Loligo duvauceli. LOLDUVIN-S: 'Lol' stands for Loligo and 'duvin' stands for a protein from the species of Loligo duvauceli. 'S' stands for the discoverer's [my] name 'SMILINE' This is the first study to design the preliminary protocols for isolation and identification of Lolduvin-S by electrophoresis method. Lolduvin-S was found to possess a molecular weight of 63Kda and has L- amino acid oxidase activity. Lolduvin-S possess various bioactive properties like antibacterial, antifungal, antiviral, antimalarial, immunomodulating, cytotoxic [antitumour] and was found to be biocompatible. Lolduvin-S is cost effective and can be used as novel therapeutic agent from a marine source in the eradication of the drug resistant micro organisms and can be designed as a drug in near future with broad spectrum bio-activity.[IN-CHE-2012-00481A]