OBTAINING AND DESIGNING A COMPOUND WITH ANTINEOPLASTIC ACTIVITY AGAINST LEUKEMIA AND CERVICAL CANCER.

摘要

The present disclosure is related to the preparation of a pharmaceutical composition for the inhibition of recombinant human histone deacetylase 6 with antineoplastic activity on cervical cancer cells, acute myeloid leukemia, human mastocytic leukemia and chronic myeloid leukemia. Consisting of an acid derivative of phenylbutyric acid with the carboxyl group modified by the addition of an aromatic ring monosubstituted by chlorine in para position (forming an amide).