Use of a mixture of two or more enteric materials to regulate drug release through a membrane or matrix for systemic therapies

摘要

Pharmaceutical composition comprising a matrix dosage form containing at least one active agent distributed in a controlled release matrix comprising a combination of more than two enteric materials, in which the active principle or principles have a release profile that is dependent on the pH and at least two of said enteric materials dissolve at a different pH in the intestine.