Pharmaceutical composition for the treatment of diseases of the central and peripheral nervous system of vascular, traumatic, toxic, hypoxic and autoimmune origin

摘要

Pharmaceutical composition for use in the treatment of diseases of the central and peripheral nervous system, of vascular, traumatic, toxic, hypoxic and autoimmune origin, in the form of a solution for parenteral, intranasal and subconjunctival administration; in which the active ingredient is the biologically active protein-polypeptide complex of 0.01 to 2.0 mg / ml with the specific reparative effect of the tissue on the nervous tissue, obtainable from the rapidly frozen embryonic brain tissue of mid-first cattle third to the middle of the last third of gestational age, a complex that contains weakly acidic neutral proteins and polypeptides with a negative charge in relation to growth factor, differentiation factor, signaling molecules, which determine their biological and pharmacological activity, with masses molecules of 5 to 200 kDa, in which at least 80% of the total protein mass has the molecular mass of 10 to 120 kDa, and is characterized by a peak in the wavelength of 274-284 nm in the UV spectrum -visible and bands in the range of 4.2 to 8.4 in isoelectric focus on a 5% polyacrylamide gel, and complex containing a pharmaceutically acceptable diluent.