CD127 expression that correlates inversely with FoxP3 and the Treg CD4 + suppressor function

摘要

A method of preparing a population of isolated immunosuppressive regulatory T cells, said method comprising: selecting a sample comprising T cells by the expression levels of a set of markers consisting of CD4, CD127 and CD25 to detect CD4 + CD127lo / T cells. -CD25 +; and isolating the detected CD4 + CD127lo / -CD25 + T cells to provide the population of isolated immunosuppressive regulatory T cells, wherein the population comprises at least 103 immunosuppressive regulatory T cells.