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DENGUE VIRUS RECOMBINANT ANTIGEN AND PREPARATION METHOD AND APPLICATION OF SAME

机译:登革病毒重组抗原及其制备方法和应用

摘要

The present invention discloses a dengue virus recombinant antigen and a preparation method and an application of the same. The dengue virus recombinant antigen comprises: (a) a polypeptide composed of the amino acid sequence shown by SEQ ID No. 1; and (b) a polypeptide having at least 98% homology with the polypeptide composed of the amino acid sequence shown by SEQ ID No. 1; or (c) a polypeptide obtained by deletion, replacement, or addition of one or more amino acids of the polypeptide composed of the amino acid sequence shown by SEQ ID No. 1. As verified by tests, a test kit prepared with this dengue virus recombinant antigen can accurately detect samples infected with four serotype dengue viruses. Therefore, this dengue virus recombinant antigen can be used for dengue fever detection.
机译:本发明公开了一种登革病毒重组抗原及其制备方法和应用。登革热病毒重组抗原包括:(a)由SEQ ID No.1所示的氨基酸序列组成的多肽; (b)与由SEQ ID No.1所示的氨基酸序列组成的多肽具有至少98%同源性的多肽; (c)通过缺失,置换或添加由SEQ ID No.1所示的氨基酸序列组成的多肽的一个或多个氨基酸获得的多肽。经测试证实,用该登革热病毒制备的测试试剂盒重组抗原可以准确检测出感染了四种血清型登革热病毒的样品。因此,该登革热病毒重组抗原可用于登革热检测。

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