IMPLANTED FLEXIBLE NEURAL MICROELECTRODE COMB, AND PREPARATION METHOD AND IMPLANTATION METHOD THEREFOR

摘要

Disclosed are an implanted flexible neural microelectrode comb, and a preparation method and implantation method therefor. The flexible neural microelectrode comb is mainly composed of a flexible substrate layer (1), a flexible insulation layer (2), and a metal connection wire layer (3) arranged between the flexible substrate layer (1) and the flexible insulation layer (2); the flexible neural microelectrode comb comprises a comb tooth-like structure (4), a grid structure (5), a solid structure (6) and a welding pad (7) connected in sequence; electrode sites (8) are arranged on the comb tooth-like structure (4); welding points are arranged on the welding pad (7); the metal connection wire layer (3) is composed of metal connection wires connecting the electrode sites (8) and the welding points; and the flexible insulation layer (2) is arranged on the surfaces of the electrode sites (8) and the welding points. The prepared flexible neural microelectrode comb has a structure gradually changing from a wire to a grid to a plane, thus improving mechanical stability during a deformation process. The mechanical properties of the implanted flexible neural microelectrode comb match brain tissue, the implantation area is small, an inflammatory response of the brain is avoided, and electroencephalograph signals can be stably tracked and measured in a multi-point manner for a long time.