首页> 外国专利> 2- Composition for preventing improving or treating hepatic steatosis or nonalcoholic fatty liver comprising enzyme degrading 2-monoacylglycerol

2- Composition for preventing improving or treating hepatic steatosis or nonalcoholic fatty liver comprising enzyme degrading 2-monoacylglycerol

机译:2-用于预防或改善肝脂肪变性或非酒精性脂肪肝的组合物,其包含降解2-单酰基甘油的酶

摘要

The present invention relates to a composition for preventing, alleviating or treating a metabolic syndrome comprising 2-monoacylgycerol lyase. The composition completely decomposes triglyceride into fatty acid and glycerol in a digestive tract to delay a fat absorption and reduce insorption of the triglyceride, and also decomposes monoacylglycerol into monoacylglycerol lipase in the digestive tract to delay the triglyceride recombination in digestive epithelial cells or to accelerate energy consumption of the process even if fat is absorbed. Therefore, the composition can be used as prevention or treatment for the hepatic steatosis, nonalcoholic fatty liver, hyperlipidimia, type 2 diabetes mellitus, and/or obesity.
机译:本发明涉及用于预防,减轻或治疗代谢综合症的组合物,其包含2-单酰基甘油裂合酶。该组合物在消化道中将甘油三酸酯完全分解为脂肪酸和甘油,以延迟脂肪吸收并减少甘油三酸酯的吸收,并且还在消化道中将单酰基甘油分解为单酰基甘油脂酶,以延迟甘油三酯在消化道上皮细胞中的重组或加速能量的吸收。即使吸收了脂肪也消耗了该过程。因此,该组合物可用作肝脂肪变性,非酒精性脂肪肝,高脂血症,2型糖尿病和/或肥胖症的预防或治疗。

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