首页> 外国专利> HAIR GROWTH-INDUCING COMPOSITION COMPRISING EXOSOMES DERIVED FROM HUMAN ADIPOSE STEM CELLS AND HUMAN DERMAL PAPILLA CELLS

HAIR GROWTH-INDUCING COMPOSITION COMPRISING EXOSOMES DERIVED FROM HUMAN ADIPOSE STEM CELLS AND HUMAN DERMAL PAPILLA CELLS

机译:包含源自人脂肪干细胞和人真皮乳头状细胞的外显子的诱导毛发生长的组合物

摘要

The present invention relates to a composition for a therapeutic agent for preventing hair loss and promoting hair growth, containing a mixture of exosomes extracted from human dermal papilla cells and human adipose stem cells involved in hair restoration. The exosomes of the present invention are exosomes that are secreted during cell proliferation, and contain genes, proteins, and growth factors involved in cell proliferation, differentiation and restoration of stem cells, and thus can induce hair restoration without using other additives such as cell activators or growth factors. Further, since the exosomes are a refined substance not containing harmful factors in antibiotics, serum, and culture fluid, the problems of therapeutic agents using culture fluid can be overcome, and furthermore, the exosomes, for being a cell-derived lipid carrier, show excellent efficiency for penetrating cells and delivering effective factors. Accordingly, the present invention may be applicable as a hair loss treatment agent and a scalp treatment/hair restoration aid intended for inducing proliferation of human dermal papilla cells and hair growth-related cells, and enhancing hair restoration.;COPYRIGHT KIPO 2018
机译:本发明涉及用于预防脱发和促进头发生长的治疗剂的组合物,该组合物含有从人毛乳头细胞和人脂肪干细胞中提取的与毛发修复有关的外泌体的混合物。本发明的外泌体是在细胞增殖期间分泌的外泌体,并且包含与细胞增殖,干细胞的分化和恢复有关的基因,蛋白质和生长因子,因此可以在不使用其他添加剂例如细胞激活剂的情况下诱导头发恢复。或成长因素。此外,由于外泌体是不含抗生素,血清和培养液中的有害因子的精制物质,因此可以克服使用培养液的治疗剂的问题,此外,作为细胞来源的脂质载体的外泌体显示出穿透细胞和传递有效因子的出色效率。因此,本发明可用作脱发治疗剂和头皮治疗/毛发恢复辅助剂,旨在诱导人真皮乳头细胞和毛发生长相关细胞的增殖并增强毛发的恢复.COPYRIGHT KIPO 2018

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