The present invention relates to a mating connection device (1) comprising a line connecting link (10) and a wind guard (50), wherein the line connecting link (10) comprises first and second (11, 12). The locking means 13 of the first coupling element 11 thereby engage the second coupling element 12. The wind guard 50 has a plastic envelope 51 that includes a first portion envelope 52 and a second partial envelope 53 that are positioned opposite each other at the split plane T (54) and form first and second line openings (55,56), which connect the receiving space (54) to the enclosing area (U) outside the receiving space (54). The first engagement element 11 is engaged with the first partial shell 52 and / or the second partial shell 53 by mutual locking engagement in an axial fixed manner in the axial direction A in the receiving space 54 do. The actuating means 57,58 can be actuated by the movement of the wind guard 50 in the axial direction A and away from the second engaging element 12, The actuating means 57,58 are coupled to the capturing means 13 in such a way that the engaging element 11 can be separated from the second engaging element 12. [
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机译: 6.一种化合物,其包含具有根据20的EP-B1-2563920(SEQ ID NO:80)的具有由20个连接的核苷组成的核碱基序列的修饰的寡核苷酸,其中所述修饰的寡核苷酸包含:由十个连接的脱氧核苷组成的缺口片段;和由五个连接的核苷组成的5'翼区段; 3'翼段由五个连接的核苷组成;其中所述间隙片段位于5'侧翼片段和3'侧翼片段之间,其中每个侧翼片段的每个核苷包含2'-O-甲氧基乙基糖;其中修饰的寡核苷酸的每个胞嘧啶是5-甲基胞嘧啶,并且其中修饰的寡核苷酸的每个核苷间键是硫代磷酸酯键;特别是inotersen;及其衍生物,例如由EP-B1-2563920保护的其盐,包括钠盐。