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Compositions and methods for acutely boosting nitric oxide levels

机译:急剧增加一氧化氮水平的组合物和方法

摘要

Compositions and methods for acutely raising nitric oxide levels in an individual are disclosed herein. In one example, the composition comprises an NOS-dependent source of an effective amount of nitric oxide; An NOS independent source of effective amount of nitric oxide; And an effective amount of a bone marrow cell type peroxidase inhibitor; Wherein the composition acutely elevates the nitric oxide level in the individual to a level exceeding that provided by the available source of nitric oxide in the subject prior to administration of the composition. Methods of treating an individual for a disease or disorder responsive to nitric oxide therapy are also provided and are disclosed herein to provide a method of treating a disease or disorder responsive to a nitric oxide therapy, Acute elevation of nitric oxide levels.
机译:本文公开了用于急性升高个体中一氧化氮水平的组合物和方法。在一个实例中,该组合物包含有效量一氧化氮的NOS依赖性源;和NOS独立来源的有效量一氧化氮;有效量的骨髓细胞型过氧化物酶抑制剂;其中所述组合物将个体中的一氧化氮水平急剧升高至超过受试者在施用所述组合物之前可利用的一氧化氮源提供的水平。还提供了治疗个体对一氧化氮疗法有响应的疾病或病症的方法,并在本文中公开以提供治疗对一氧化氮疗法有响应的疾病或病症的方法,急性升高一氧化氮水平。

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