ESBL ECO4 Novel ESBL producing Escherichia coli specific bacteriophage ECO4 and antibacterial composition comprising the same

摘要

The present invention relates to a novel bacteriophage ECO4 having a killing ability specific to Escherichia coli, particularly ESBL producing Escherichia coli; an antibiotic composition, a feed additive composition, a feed, a disinfectant or a washing agent, which all include the bacteriophage; and a method for preventing or treating infectious diseases caused by ESBL producing Escherichia coli, which includes a step of administrating the bacteriophage to an object. The method for preventing or treating infectious diseases caused by ESBL producing Escherichia coli using the bacteriophage ECO4 has very high specificity to salmonella compared to a conventional chemical material such as antibiotics or the like, and the bacteriophage ECO4 is infected to ESBL producing Escherichia coli to proliferate in the ESBL producing Escherichia coli, thereby having excellent bacteriolytic activity and being strong to physiochemical stimulation. In addition, the bacteriophage ECO4 of the present invention is not infected to a host other than bacteria except a human, an animal, a plant, or the like, and thus it is possible to solve a problem of antibiotic resistant bacteria due to abuse of antibiotics, a problem of residual antibiotics in food, and a problem of a wide range of host ranges. Accordingly, the bacteriophage ECO4 of the present invention can be variously used in the fields of prevention or treatment of infectious diseases caused by ESBL producing Escherichia coli, antibiotic compositions, feed additive compositions, feeds, disinfectants, or washing agents.