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5-HT4 5---8- 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS

机译：5-HT4 5 --- 8- 5-氨基-喹啉-8-羧酰胺衍生物作为5-HT4受体激动剂

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摘要

The present invention relates to novel quinoline compounds of the formula ( I ) and their pharmaceutically acceptable salts and processes for their preparation. The compounds of formula ( I ) are useful for the treatment of various diseases associated with 5-HT ₄ receptor agonists.

机译：本发明涉及式（ I ）的新型喹啉化合物及其药学上可接受的盐和其制备方法。式（ I ）化合物可用于治疗与5-HT _{4 受体激动剂有关的各种疾病。} 展开▼

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公开/公告号KR101815307B1

专利类型

公开/公告日2018-01-04

原文格式PDF

申请/专利权人 수벤 라이프 사이언시스 리미티드;
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申请/专利号KR20157030158

发明设计人 니로기 라마크리쉬나;쉰데 아닐 카르바리;자스티 벤카테스와를루;
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申请日2013-10-18

分类号C07D401/12;A61K31/4709;C07D405/14;G01N33/558;G01N33/574;

国家 KR

入库时间 2022-08-21 12:38:39

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1. 作为5-HT4受体激动剂的5-氨基-喹啉-8-甲酰胺衍生物 [P] . 中国专利： CN105164119A . 2015-12-16

2. 作为5－HT4受体配位体的5－芳基－3－(8－氮杂双环3.2.2辛－3－基)－1,3,4－噁二唑基－2(3H)酮衍生物 [P] . 中国专利： CN1260794A . 2000-07-19

3. 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS. [P] . MX364929B . 2019-05-14

机译： 5-氨基-喹啉-8-羧酰胺衍生物为5-HT4受体激动剂。

4. 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS [P] . CA2907620C . 2018-03-13

机译： 5-氨基-喹啉-8-羧酰胺衍生物作为5-HT4受体激动剂

5. 5-Amino-quinoline-8-carboxamide derivatives as 5-HT4 receptor agonists [P] . ES2674993T3 . 2018-07-05

机译： 5-氨基喹啉-8-羧酰胺衍生物作为5-HT4受体激动剂

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3. Effects of 5-HT2B, 5-HT3 and 5-HT4 receptor antagonists on gastrointestinal motor activity in dogs [J] . Hiroki Morita ,Erito Mochiki ,Nobuyuki Takahashi . 世界胃肠病学杂志：英文版 . 2013,第39期

4. Lack of Effect of the 5-HT4 Receptor Ligands RS 67333 and RS 39604 on Murine Agonistic Behaviour [J] . Robert Bell ,Karl Lynch . 行为与脑科学期刊（英文） . 2012,第1期

5. 5-HT4受体激动剂联合西甲硅油治疗非溃疡性消化不良的效果观察 [J] . 谭林 ,杨培 . 广东医学 . 2021,第003期

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