Fraction of Zanthoxylum piperitum leaf extracts with the effect of analgesic

摘要

The present invention relates to a pain composition comprising a fraction obtained by solvent fractionation of a leaf extract of Zanthoxylum piperitum . More specifically, the solvent fraction isolated from the leaves of papaya suppresses both pain, inflammation and arthritis in a pain-induced animal model, an inflammation-inducing model, and an arthritis-inducing model, and exhibits a very good expression and inhibition pattern on the molecular indicators thereof. And as an effective pharmaceutical composition for the treatment of inflammation-based arthritis.