PCR A method for prenatal diagnosis using digital PCR

摘要

The present invention relates to a prenatal diagnosis method using digital PCR. The existing amniocentesis method for the prenatal diagnosis is an invasive test, and there are risks such as bacterial infection of the amniotic membrane by the syringe, wound by the syringe, leakage of the amniotic fluid. Recently, fetal DNA is obtained from the blood of pregnant women to diagnose fetal genetic abnormality, but the blood of pregnant women contains only a very small amount of fetal DNA compared to maternal DNA analysis of fetal genetic information is accurate This is a very bad situation. Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made in order to solve the above-mentioned problems of the prior art, and it is a method for enhancing the accuracy of fetal genetic information analysis by concentrating fetal DNA during prenatal diagnosis using blood of a pregnant woman. The prenatal diagnosis method of the present invention is expected to be widely used in the field of prenatal diagnosis since it is safe, simple and reliable in both pregnancy and fetus.