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PCR A method for prenatal diagnosis using digital PCR
PCR A method for prenatal diagnosis using digital PCR
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机译:PCR一种使用数字PCR进行产前诊断的方法
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摘要
The present invention relates to a prenatal diagnostic method using digital PCR. The conventional amniotic fluid puncture method for prenatal diagnosis is an invasive test, and there is a risk of bacterial infection of the amniotic membrane with a syringe, a wound problem with a syringe, and a leak of amniotic fluid. Therefore, recently, a method of diagnosing genetic abnormalities of fetuses by obtaining fetal DNA from maternal blood has been introduced. However, since fetal DNA contains only a very small amount of fetal DNA compared to maternal DNA, fetal genetic information analysis is not accurate. It is very low. The present invention has been made to solve the above conventional technical problems, it is a method that can improve the accuracy of fetal genetic information analysis by concentrating fetal DNA during prenatal diagnosis using pregnant women's blood. The antenatal diagnostic method of the present invention is safe, simple, and reliable for both pregnant and fetus, and is expected to be widely utilized in the field of antenatal diagnosis.
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