Time-Multiplexed Structured Illumination with Digital Micromirror Device for Structured Illumination Microscopy and Method of Operating the same

摘要

A structured illumination microscope system using a digital micromirror element and time-complex structured illumination and a method of operation thereof are provided. In one embodiment, a structured illumination microscope system using a digital micromirror element and time-complex structured illumination includes a light source; A digital micromirror device (DMD) configured to receive the light irradiated from the light source and implement time-complex structured illumination to inject the controlled structured illumination into a sample; And a fluorescence image measuring unit extracting a high resolution 3D fluorescence image of the sample.