首页> 外国专利> 6- (3,5-diphenyl-1,3,4-thiadiazole-2 (3H) -ilidene) -2,4-diphenyl-4H-1,3,4-thiadiazin-5-one and method for preparing it

6- (3,5-diphenyl-1,3,4-thiadiazole-2 (3H) -ilidene) -2,4-diphenyl-4H-1,3,4-thiadiazin-5-one and method for preparing it

机译:6-(3,5-二苯基-1,3,4-噻二唑-2(3H)-二烯烃)-2,4-二苯基-4H-1,3,4-噻二嗪-5-酮及其制备方法

摘要

FIELD: chemistry.SUBSTANCE: invention relates to organic and medical chemistry, namely to 6-(3,5-Diphenyl-1,3,4-thiadiazol-2(3H)-ylidene)-2,4-diphenyl-4H-1,3,4-thiadiazin-5-one of the formula I. Invention also relates to a process for its preparation. Process is carried out by reacting thiadiazole with sodium hydroxide followed by oxidative cyclisation with air oxygen. And thiadiazole is boiled with sodium hydroxide in a water-alcohol medium with a reflux condenser, then the reaction mass is kept in air at room temperature, followed by isolation of the desired product..EFFECT: technical result is preparation of a new chemical compound that can be used in medicine as a potential antimicrobial agent.3 cl, 1 dwg, 2 ex, 4 tbl
机译:技术领域本发明涉及有机和医学化学,即6-(3,5-二苯基-1,3,4-噻二唑-2(3H)-亚烷基)-2,4-二苯基-4H-1式I的,3,3,4-噻二嗪-5-酮。本发明还涉及其制备方法。该方法通过使噻二唑与氢氧化钠反应,然后与空气氧进行氧化环化来进行。然后将噻二唑与氢氧化钠在带有回流冷凝器的水醇介质中煮沸,然后将反应物料在室温下保持在空气中,然后分离出所需的产物。效果:技术成果是制备了一种新的化合物可用于医学中作为潜在的抗菌剂.3 cl,1 dwg,2 ex,4 tbl

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