.;EFFECT: technical result is preparation of a new chemical compound that can be used in medicine as a potential antimicrobial agent.;3 cl, 1 dwg, 2 ex, 4 tbl"/> 6-(3,5-DIPHENYL-1,3,4-THIADIAZOL-2(3H)-YLIDEN)-2,4-DIPHENYL-4H-1,3,4-THIADIAZIN-5-ONE AND METHOD OF ITS PRODUCTION
首页> 外国专利> 6-(3,5-DIPHENYL-1,3,4-THIADIAZOL-2(3H)-YLIDEN)-2,4-DIPHENYL-4H-1,3,4-THIADIAZIN-5-ONE AND METHOD OF ITS PRODUCTION

6-(3,5-DIPHENYL-1,3,4-THIADIAZOL-2(3H)-YLIDEN)-2,4-DIPHENYL-4H-1,3,4-THIADIAZIN-5-ONE AND METHOD OF ITS PRODUCTION

机译:6-(3,5-二苯并-1,3,4-噻二唑-2(3H)-亚烷基)-2,4-二苯并-4H-1,3,4-噻二嗪-5-一及其生产方法

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to organic and medical chemistry, namely to 6-(3,5-Diphenyl-1,3,4-thiadiazol-2(3H)-ylidene)-2,4-diphenyl-4H-1,3,4-thiadiazin-5-one of the formula I. Invention also relates to a process for its preparation. Process is carried out by reacting thiadiazole with sodium hydroxide followed by oxidative cyclisation with air oxygen. And thiadiazole is boiled with sodium hydroxide in a water-alcohol medium with a reflux condenser, then the reaction mass is kept in air at room temperature, followed by isolation of the desired product. .;EFFECT: technical result is preparation of a new chemical compound that can be used in medicine as a potential antimicrobial agent.;3 cl, 1 dwg, 2 ex, 4 tbl
机译:技术领域本发明涉及有机和医学化学,即6-(3,5-二苯基-1,3,4-噻二唑-2(3H)-亚烷基)-2,4-二苯基-4H-式I的1,3,4-噻二嗪-5-酮。本发明还涉及其制备方法。该方法通过使噻二唑与氢氧化钠反应,然后与空气氧进行氧化环化来进行。然后将噻二唑与氢氧化钠在带有回流冷凝器的水醇介质中煮沸,然后将反应物料在室温下保持在空气中,然后分离出所需的产物。 。;效果:技术成果是制备了可用于医学的新化合物作为潜在的抗菌剂。; 3 cl,1 dwg,2 ex,4 tbl

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