首页> 外国专利> METHOD OF DIAGNOSTICS OF PREDISPOSITION TO PROGRESSION OF ATHEROSCLEROSIS OF CAROTID ARTERIES IN PERSONS WITH NORMOLIPIDEMIA ON CONTENT OF CD4 + T-LYMPHOCYTES IN PERIPHERAL BLOOD

METHOD OF DIAGNOSTICS OF PREDISPOSITION TO PROGRESSION OF ATHEROSCLEROSIS OF CAROTID ARTERIES IN PERSONS WITH NORMOLIPIDEMIA ON CONTENT OF CD4 + T-LYMPHOCYTES IN PERIPHERAL BLOOD

机译:血脂异常患者外周血CD4 + T淋巴细胞含量的易发性颈动脉粥样硬化诊断方法

摘要

FIELD: medicine.;SUBSTANCE: invention can be used to diagnose predisposition to the progression of carotid atherosclerosis in patients with concentration of low-density lipoproteins cholesterol (LDL cholesterol) 3.5 mm (normolipidemia). The method includes sample analysis to determine the population of CD4 + T-lymphocytes, featuring those that phenotyping of lymphocytes is made using labelled with fluorescent labels monoclonal antibodies to CD4, wherein the content of CD4 + cells, expressed in percentage (%) respect of lymphocytes, more than 39.5% indicates a high risk of progression of atherosclerosis.;EFFECT: use of this method allows to identify patients with high risk of progression of atherosclerosis, which allows timely correction of therapy in this category of patients.;2 ex, 1 tbl, 1 dwg
机译:领域:药物;发明:本发明可用于诊断浓度<3.5 mm的低密度脂蛋白胆固醇(LDL胆固醇)患者的颈动脉粥样硬化进展的易感性(血脂异常)。该方法包括样品分析以确定CD4 + T淋巴细胞的数量,其特征在于使用荧光标记的针对CD4的单克隆抗体标记淋巴细胞的表型,其中CD4 + T细胞的含量,以相对于超过39.5%的淋巴细胞表示动脉粥样硬化进展的高风险。;效果:使用此方法可以识别出动脉粥样硬化进展的高风险的患者,从而可以及时纠正此类患者的治疗方法; 2 ex, 1桶,1桶

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